FXYD7 Antibody | 6465

FXYD7 Antibody | 6465 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (71%)

Immunogen: FXYD7 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human FXYD7.
The immunogen is located within the first 50 amino acids of FXYD7.

Research Area: Neuroscience

Tested Application: E, WB, IHC-P, IF

Application: FXYD7 antibody can be used for detection of FXYD7 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Specificiy: FXYD7 antibody is human, mouse and rat reactive. FXYDY7 antibody is predicted to not react with other members of the FXDY protein family

Positive Control 1: Cat. No. 1302 - Human Lung Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: FXYD7 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: FXYD7 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: FXYD7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: FXYD7 Antibody: FXYD domain-containing ion transport regulator 7

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FXYD7 Antibody: FXYD7 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing seven invariant and six highly conserved amino acids. The FXYD proteins are tissue-specific regulators of Na, K-ATPase, with FXYD7 initially identified as a brain-specific member. FXYD7 interacts with Na, K-ATPase through its transmembrane domain and is thought to influence the affinity of Na, K-ATPase for external K+ and Na+ ions. Other members of the FXDY family have similar functions: FXYD2 regulates the properties of Na, K-ATPase, while FXYD1 (phospholemman) , FXYD3 (MAT-8) , FXYD4 (CHIF) , and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems.