Additional Information
Size: |
100 µl |
Target: |
Fyn (pTyr530) |
Conjugate: |
FITC |
Research Area: |
Neuroscience | Neurodegeneration | Alzheimer's Disease | Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | Src Family | Cancer | Tumor Biomarkers | Oncoproteins | Signal Transducers |
Alternative Name: |
Proto oncogene tyrosine protein kinase fyn Antibody, Proto-oncogene c-Fyn Antibody, SLK Antibody, FYN oncogene related to SRC FGR YES Antibody, Src yes related novel gene Antibody, Protein tyrosine kinase fyn Antibody, Src like kinase Antibody, Fyn A |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530). |
Immunogen Species: |
Human |
Applications: |
WB, IHC, ELISA |
Host: |
Rabbit |
Isotype: |
IgG |
Species Reactivity: |
Human, Mouse |
Antibody Dilution: |
WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide |
Concentration: |
N/A |
Specificity: |
Detects endogenous levels of Fyn only when phosphorylated at tyrosine 530 (pTyr530). |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
A 1:500 dilution of SPC-1383 was sufficient for detection of Fyn (pTyr530) in 10 µg of human embryonic kidney epithelial cell line (hek293) lysate by ECL immunoblot analysis using goat anti-rabbit as the secondary antibody. |
Cellular Localization: |
Plasma Membrane, Cell Membrane, Nucleus, Cytoplasm, Cytoskeleton, Actin Filament, Cytosol, Endosome, Mitochondrion, Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane, Dendrite, Membrane Raft |
Tissue Specificity: |
Isoform 1 is highly expressed in the brain. Isoform 2 is expressed in cells of hemopoietic lineages, especially T-lymphocytes. |
Accession Number: |
NP_002028.1 |
Gene ID: |
2534 |
Swiss-Prot: |
P06241 |
Field of Use: |
For in vitro research use only. |