GABA A Receptor α5 polyclonal Antibody | BS90550

GABA A Receptor α5 polyclonal Antibody | BS90550 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IF IHC

Application Range: ICC/IF:1:50-1:200 IHC:1:50-1:200 WB:1:500

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid) . In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3) . The GABA transporters function to terminate GABA action.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: GABA A Receptor α5 polyclonal Antibody detects endogenous levels of GABA A Receptor α5 protein.

Molecular Weight: 52 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GABRA5, GAA 5, GAA5, GABA (A) receptor subunit alpha-5, GABRA 5, Gabra5, Gamma aminobutyric acid GABA A receptor alpha 5, Gamma aminobutyric acid GABA A receptor alpha 5 precursor, Gamma aminobutyric acid receptor alpha 5 subunit precursor GABA A receptor, Gamma-aminobutyric acid receptor subunit alpha-5, GBRA5, GC138184,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: