Galectin-1, human recombinant | 4648

Galectin-1 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of -galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs). Galectin-1 has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds -galactoside as well as CD45, CD3 and CD4. Recombinant Human Galectin is a 14.5 kDa protein consisting of 134 amino acid residues.

4648 | Galectin-1 human recombinant DataSheet

Biomolecule/Target: Galectin-1

Synonyms: Galectin-1, Lectin galactoside-binding soluble 1, -galactoside- binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, Putative MAPK-activating protein PM12, GBP, DKFZp686E23103

Alternates names: Mammotropin, Luterotropic hormone, Lutetropin, Prlr, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R

Taglines: Modulates cell–cell and cell–matrix interactions

NCBI Gene ID #: 256249

NCBI Gene Symbol: PRL

Gene Source: Human

Accession #: P06879

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: The ED determined by the dose-dependent stimulation of the proliferation of rat lymphoma, Nb2-11 cells was found to be in the range of 0.1-1.0 ng/ml.

Results: 2.5 µg/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 22.5 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized from 20 mM Tris, pH 7.5.

Reconstitution Instructions: Reconstitute in HO to a concentration of 1.0 mg/ml. This solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A