Gallein | B3391

Gallein | B3391

Description: Gallein is an inhibitor of G protein βγ subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells. It inhibits metastatic spread of tumor cells expressing OR51E2 and exposed to its odorant ligand.

Alternate Name/Synonyms: 3',4',5',6'-Tetrahydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one

Appearance: Black solid

Formulation:

CAS Number: 2103-64-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₂O₇

Molecular Weight: 364.31

Cell-Permeable?: True

Purity: ≥97%

Solubilities: >25 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Tag Line: Inhibitor of Gβ/γ signaling

PubChem CID: 73685

PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/73685

SMILES: OC1=CC=C(C(C(C=CC=C5)=C5C(O4)=O)4C(C=CC(O)=C3O)=C3O2)C2=C1O

InChi: InChI=1S/C20H12O7/c21-13-7-5-11-17(15(13)23)26-18-12(6-8-14(22)16(18)24)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,21-24H

InChi Key: PHLYOKFVXIVOJC-UHFFFAOYSA-N

Category: Biochemicals