Ganciclovir | 1918

An acyclic analog of the nucleoside guanosine, chemically related to acyclovir. It inhibits the replication of viruses including CMV, Herpes Simplex, Varicella Zoster and Epstein-Barr. It inhibits virus replication by its incorporation into viral DNA. This incorporation inhibits dATP and leads to defective DNA, ceasing or retarding the viral machinery required to spread the virus to other cells.

Ganciclovir is an acyclic analog of the nucleoside guanosine, chemically related to acyclovir. It inhibits the replication of viruses including CMV, Herpes Simplex, Varicella Zoster and Epstein-Barr. It inhibits virus replication by its incorporation into viral DNA. This incorporation inhibits dATP and leads to defective DNA, ceasing or retarding the viral machinery required to spread the virus to other cells.

1918 | Ganciclovir DataSheet

Alternate Name/Synonyms: 2-Amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-3H-purin-6-one

Appearance: White solid

Formulation: N/A

CAS Number: 82410-32-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₁₃N₅O₄

Molecular Weight: 255.23

Cell-Permeable?: No

Purity: ≥98% by HPLC

Solubilities: DMSO (~5 mg/ml) or H₂O (~ 2 mg/ml)

Handling: Protect from air and mositure

Country of Origin: USA

Tag Line: An antiviral agent

MDL Number: MFCD00870588

PubChem CID: 3454

SMILES: C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N

InChi: InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)

InChi Key: IRSCQMHQWWYFCW-UHFFFAOYSA-N