BW
GATA-6 (R493) polyclonal Antibody | BS9273
- SKU:
- BW-BS9273
- Availability:
- Usually ships in 5 working days
Description
GATA-6 (R493) polyclonal Antibody | BS9273 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T-lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4, expression.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GATA-6 (R493) polyclonal Antibody detects endogenous levels of GATA-6 protein.
Molecular Weight: ~ 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Gata binding factor 6; Gata binding protein 6; GATA-binding factor 6; Gata6; Transcription factor Gata 6; Transcription factor GATA-6;
Immunogen: Synthetic peptide, corresponding to amino acids 460-510 of Human GATA-6.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: