GCNT1 Polyclonal Antibody | BS65721

GCNT1 Polyclonal Antibody | BS65721 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,

Application: WB,

Application Range: WB=1:500-2000

Background: GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GCNT1 Polyclonal Antibody detects endogenous levels of GCNT1 protein.

Molecular Weight: 52 kD，50 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase; Beta-1; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; C2GNT; C2GNT L; C2GNT1; C2GnTL; Core 2 branching enzyme; Core 2 GNT; Core 2-branching enzyme; Core2 GlcNAc transferase; Core2-GlcNAc-transferase; GCNT 1; GCNT 1; GCNT1; GCNT1_HUMAN; glucosaminyl (N-acetyl) transferase 1 core 2; NACGT2.   

Immunogen: KLH conjugated synthetic peptide derived from Human GCNT1:201-260/428

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: