GDA polyclonal Antibody | BS8219

GDA polyclonal Antibody | BS8219 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:100

Background: The assembly of neurotransmitter receptors and associated signal transduction machinery at synaptic sites involves postsynaptic density 95 (PSD-95) and related membrane-associated guanylate kinase (MAGUK) proteins. Cypin, (Cytoplasmic PSD-95 interactor, also designated guanine deaminase and nedasin S), regulates intermediate steps in postsynaptic protein sorting, such as synaptic clustering of MAGUK proteins, and associates with multiple members of the PSD-95 family . Expressed both pre- and post-synaptically, cypin is most prevalent within the cytoplasm of dendritic shafts and in the neck of synaptic spines . In non-neuronal cells, cypin is most highly expressed in the basal membrane of intestinal epithelial cells. Cypin is also highly expressed in kidney, liver, lung, brain, and spleen, with lower levels of expression in placenta, heart, and skeletal muscle . Native cypin may also be expressed as a dimer and a tetramer .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GDA polyclonal Antibody detects endogenous levels of GDA protein.

Molecular Weight: ~ 51 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CYPIN; Cytoplasmic PSD95 interactor; D10S105E; GAH; GDA; GUAD_HUMAN; Guanase; Guanine aminase; Guanine aminohydrolase; Guanine deaminase; MGC9982; NEDASIN; p51-nedasin; SLC25A16

Immunogen: Recombinant full length Human GDA.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Ubiquitin Proteasome,