GDC0879 | B1340

A novel, potent, and selective inhibitor of B-Raf with an IC50 value of 0.13 nM

A novel, potent, and selective inhibitor of B-Raf with an IC50 value of 0.13 nM

B1340 | GDC0879 DataSheet

Alternate Name/Synonyms: 2-[4-[(1E)-1-hydroxyimino-2,3-dihydroinden-5-yl]-3-pyridin-4-ylpyrazol-1-yl]ethanol

Appearance: Solid

Formulation: N/A

CAS Number: 905281-76-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C19H18N4O2

Molecular Weight: 334.37

Cell-Permeable?: Yes

Purity: >98% by HPLC

Solubilities: DMSO > 10 mM

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A novel, potent, and selective inhibitor of B-Raf with an IC50 value of 0.13 nM

MDL Number: MFCD16875916

PubChem CID: 11717001

SMILES: C1CC(=NO)C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO

InChi: 1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,24-25H,2,4,9-10H2/b22-18+

InChi Key: DEZZLWQELQORIU-RELWKKBWSA-N