GDE1 Antibody [AMM22285G]

GDE1 Antibody [AMM22285G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This GDE1 antibody is generated from a mouse immunized with a recombinant protein from the human region of human GDE1.

Cellular Localisation: Cell membrane {ECO:0000250|UniProtKB:Q9JL55}; Multi-pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9JL55}; Multi-pass membrane protein. Note=Perinuclear vesicles and cell membrane {ECO:0000250|UniProtKB:Q9JL55}

Molecular Weight: 37718

Clone: Monoclonal

Gene Name: GDE1 (HGNC:29644)

Gene ID: 51573

Function: Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol (By similarity) . Hydrolyzes glycerophospho-N-acylethanolamines to N- acylethanolamines in the brain and partipates to bioactive N- acylethanolamines biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N- oleoylethanolamine (an anorexic) . In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl- lysoPlsEt) to N-acylethanolamine. However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity (By similarity) . Has little or no activity towards glycerophosphocholine (By similarity) .

Summary: Tissue Location: Widely expressed..

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Glycerophosphodiester phosphodiesterase 1, 3.1.4.44, Membrane-interacting protein of RGS16, RGS16-interacting membrane protein, GDE1, MIR16