GDF-3, human recombinant | 4757

GDF-3 is a member of the TGF- superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF- family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type-2 diabetes. Recombinant human GDF-3 contains 114 amino acids polypeptide chains

4757 | GDF-3 human recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: Growth/Differentiation Factor-3

Alternates names: Apolipoprotein E3, APOE, apolipoprotein, apolipoproteins

Taglines: A protein which both inhibits and induces early stages of development in embryos

NCBI Gene ID #: 348

NCBI Gene Symbol: APOE

Gene Source: Human

Accession #: NM_000041

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: Test in process

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 34 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized with no additive

Reconstitution Instructions: Reconstitute in dHO to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A