Description
GDF-3 is a member of the TGF- superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF- family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type-2 diabetes. Recombinant human GDF-3 contains 114 amino acids polypeptide chains
4757 | GDF-3 human recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: Growth/Differentiation Factor-3
Alternates names: Apolipoprotein E3, APOE, apolipoprotein, apolipoproteins
Taglines: A protein which both inhibits and induces early stages of development in embryos
NCBI Gene ID #: 348
NCBI Gene Symbol: APOE
Gene Source: Human
Accession #: NM_000041
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 90%
Assay: SDS-PAGE
Purity: 98%
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: Test in process
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 34 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered and lyophilized with no additive
Reconstitution Instructions: Reconstitute in dHO to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A