Description
A potent antitumor antibiotic . Binds specifically to heat shock protein HSP90 and its GP96 homologue; inhibits protein maturation.
Geldanamycin is a potent antitumor antibiotic . Binds specifically to heat shock protein HSP90 and its GP96 homologue; inhibits protein maturation.
Alternate Name/Synonyms: Geldanomycin; U-29135
Appearance: Yellow to orange solid
Formulation: N/A
CAS Number: 30562-34-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₉H₄₀N₂O₉
Molecular Weight: 560.64
Cell-Permeable?: Yes
Purity: ≥99%
Solubilities: DMSO
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A Hsp90 inhibitor
MDL Number: MFCD00274570
PubChem CID: 5288382
SMILES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC
InChi: InChI=1S/C29H40N2O9/c1-15-11-19-25(34)20(14-21(32)27(19)39-7)31-28(35)16(2)9-8-10-22(37-5)26(40-29(30)36)18(4)13-17(3)24(33)23(12-15)38-6/h8-10,13-15,17,22-24,26,33H,11-12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8-,16-9+,18-13+/t15-,17+,22+,23+,24-,26+/m1/s1
InChi Key: QTQAWLPCGQOSGP-KSRBKZBZSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24months |
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