GFAP, Human Recombinant | P1364

Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood.

P1364 | GFAP Human Recombinant DataSheet

Biomolecule/Target: GFAP

Synonyms: Glial Fibrillary Acidic Protein, GFAP

Alternates names: Glial Fibrillary Acidic Protein, GFAP

Taglines: A class-III intermediate filament that distinguishes astrocytes from other glial cells during the development of the central nervous system

NCBI Gene ID #: 2255

NCBI Gene Symbol: FGF-10

Gene Source: Human

Accession #: O15520

Recombinant: Yes

Source: E.coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: N/A

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from a 0.2 m filtered solution of 20 mM PB, 150 mM NaCl, pH 7.25.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 µg/ml.

Amino acid sequence: MGSSHHHHHHSSGLVPRGSHMLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM