GFM1 Antibody | 19-530

GFM1 Antibody | 19-530 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 482-751 of human GFM1 (NP_079272.4) .

Research Area: Signal Transduction

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: H460

Positive Control 2: SKOV3

Positive Control 3: 293T

Positive Control 4: HeLa

Positive Control 5: Mouse liver

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 100kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: COXPD1, EFG, EFG1, EFGM, EGF1, GFM, hEFG1, mtEF-G1, elongation factor G, mitochondrial, G translation elongation factor, mitochondrial, mitochondrial elongation factor G, mitochondrial elongation factor G1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.