Description
GFM2 polyclonal Antibody | BS62364 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IF
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: Mitochondrial translation is critical for maintaining function and preventing impairment of mitochondrial DNA, with mitochondrial translation elongation factors playing an essential role in this process. EF-G2 (elongation factor G2), also known as RRF2mt (ribosome-releasing factor 2, mitochondrial), GFM2 or MSTP027, is a 779 amino acid protein belonging to the GTP-binding elongation factor family and EF-G/EF-2 subfamily. Localizing to mitochondrion, EF-G2 is widely expressed with high levels found in adult heart, skeletal muscle and kidney as well as adult and fetal liver. EF-G2 mediates ribosome recycling and by interacting directly with MRRF on the ribosome large subunit, is required for ribosome dissociation from mRNA. Existing as five alternatively spliced isoforms, the gene encoding EF-G2 maps to human chromosome 5q13.3.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GFM2 polyclonal Antibody detects endogenous levels of GFM2 protein.
Molecular Weight: ~ 95 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Ribosome-releasing factor 2, mitochondrial; RRF2mt; Elongation factor G 2, mitochondrial; EF-G2mt; mEF-G 2; Elongation factor G2; hEFG2; GFM2; EFG2; MSTP027
Immunogen: Synthetic peptide, corresponding to Human GFM2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: