GIGYF2 Antibody | 14-246

GIGYF2 Antibody | 14-246 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human GIGYF2 (NP_001096617.1) .

Research Area: Neuroscience

Tested Application: WB, IHC

Application: WB: 1:500 - 1:1000
IHC: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: HeLa

Positive Control 3: U-87MG���Jurkat

Positive Control 4: Raji

Positive Control 5: LO2

Positive Control 6: N/A

Molecular Weight: Observed: 190kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PERQ amino acid-rich with GYF domain-containing protein 2, GRB10-interacting GYF protein 2, Trinucleotide repeat-containing gene 15 protein, GIGYF2, KIAA0642, PERQ2, TNRC15

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.