GITR/TNFRSF18 Polyclonal Antibody | E-AB-66508

GITR/TNFRSF18 Polyclonal Antibody | E-AB-66508 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: TNFRSF18, AITR, CD357, GITR, GITR-D

Application: WB

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human GITR/TNFRSF18 (NP_683699.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 25 kDa/26 kDa

Molecular Weight(Observed): 30 kDa