Description
GITR/TNFRSF18 Polyclonal Antibody | E-AB-66508 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: TNFRSF18, AITR, CD357, GITR, GITR-D
Application: WB
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: N/A
Background: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human GITR/TNFRSF18 (NP_683699.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 25 kDa/26 kDa
Molecular Weight(Observed): 30 kDa