GL54D Antibody (C-term) [APR04317G]

GL54D Antibody (C-term) [APR04317G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GL54D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-372 amino acids from the C-terminal region of human GL54D.

Cellular Localisation: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q4V8F8}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q4V8F8}. Endoplasmic reticulum membrane; Single-pass type II membrane protein

Molecular Weight: 43743

Clone: Polyclonal

Gene Name: MGAT4D (HGNC:43619)

Gene ID: 152586

Function: May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.

Summary: Tissue Location: Expressed in testis. Poorly expressed in testis biopsies from men with impaired spermatogenesis

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D, 241-, MGAT4D (HGNC:43619)