GLD2 Antibody (N-term) [APR32125G]

GLD2 Antibody (N-term) [APR32125G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This GLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human GLD2.

Cellular Localisation: Cytoplasm {ECO:0000250|UniProtKB:Q91YI6}. Nucleus {ECO:0000250|UniProtKB:Q91YI6}

Molecular Weight: 56028

Clone: Polyclonal

Gene Name: TENT2 (HGNC:26776)

Gene ID: 167153

Function: Cytoplasmic poly (A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly (A) tail. In contrast to the canonical nuclear poly (A) RNA polymerase, it only adds poly (A) to selected cytoplasmic mRNAs (PubMed:15070731) . Does not play a role in replication-dependent histone mRNA degradation (PubMed:18172165) . Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs (PubMed:23200856) .

Summary: Tissue Location: Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB, IF

Dilution: IHC-P--1:100~500 IF--1:25 WB--1:1000

Synonyms: Poly (A) RNA polymerase GLD2, hGLD-2, PAP-associated domain-containing protein 4, Terminal uridylyltransferase 2, TUTase 2, PAPD4, GLD2