LBD
GLD2 Antibody (N-term) [APR32125G]
- SKU:
- LBD-APR32125G
- Availability:
- Usually ships in 5 working days
Description
GLD2 Antibody (N-term) [APR32125G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This GLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human GLD2.
Cellular Localisation: Cytoplasm {ECO:0000250|UniProtKB:Q91YI6}. Nucleus {ECO:0000250|UniProtKB:Q91YI6}
Molecular Weight: 56028
Clone: Polyclonal
Gene Name: TENT2 (HGNC:26776)
Gene ID: 167153
Function: Cytoplasmic poly (A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly (A) tail. In contrast to the canonical nuclear poly (A) RNA polymerase, it only adds poly (A) to selected cytoplasmic mRNAs (PubMed:15070731) . Does not play a role in replication-dependent histone mRNA degradation (PubMed:18172165) . Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs (PubMed:23200856) .
Summary: Tissue Location: Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, WB, IF
Dilution: IHC-P--1:100~500 IF--1:25 WB--1:1000
Synonyms: Poly (A) RNA polymerase GLD2, hGLD-2, PAP-associated domain-containing protein 4, Terminal uridylyltransferase 2, TUTase 2, PAPD4, GLD2