GLIPR1L2 Antibody | 7639

GLIPR1L2 Antibody | 7639 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: GLIPR1L2 antibody was raised against an 15 amino acid peptide near the center of human GLIPR1L2.
The immunogen is located within amino acids 120 - 170 of GLIPR1L2.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB, IHC-P, IF

Application: GLIPR1L2 antibody can be used for detection of GLIPR1L2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: GLIPR1L2 antibody is human specific. At least two isoforms of GLIPR1L2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

Positive Control 1: Cat. No. 1313 - Human Testis Tissue Lysate

Positive Control 2: Cat. No. 11-701 - Human Testis Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 28, 31, 38 kDa
Observed: 28 kDa

Validation: N/A

Isoform: N/A

Purification: GLIPR1L2 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: GLIPR1L2 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: GLIPR1L2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: GLIPR1L2 Antibody: GLIPR1-like protein 2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The GLIPR1-like 2 protein (GLIPR1L2) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (2) . GLIPR1L2 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1) . GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3) . Deletions of the GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster have been observed in some multiple myeloma samples, suggesting that these proteins may also be involved in the pathogenesis of multiple myeloma (4) .