GLP Antibody [1B7B4] | 32-161

GLP Antibody [1B7B4] | 32-161 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Ni-NTA purified truncated recombinant GLP expressed in E. Coli strain BL21 (DE3) .

Research Area: Neuroscience

Tested Application: E, WB

Application: Western Blot:Dilution 1:500 - 1:2, 000
ELISA:Propose dilution 1:10, 000.
Determining optimal working dilutions by titration test.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein A affinity chromatography.

Clonality: Monoclonal

Clone: 1B7B4

Isotype: IgG1

Conjugate: Unconjugated

Physical State: N/A

Buffer: Purified antibody in PBS containing 0.03% sodium azide.

Concentration: N/A

Storage Condition: GLP monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: EUHMTASE1, GLP, KIAA1876, KMT1D, Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, GLP1, FP13812, EUHMTASE1, bA188C12.1, RP11-188C12.1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.