Description
GLP1R Polyclonal Antibody | E-AB-62762 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: GLP1R, GLP-1, GLP-1-R, GLP-1R
Application: WB
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cardiovascular, Neuroscience
Background: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human GLP1R (NP_002053.3).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 53 kDa
Molecular Weight(Observed): 53 kDa