GLRX2 Polyclonal Antibody | E-AB-62436

GLRX2 Polyclonal Antibody | E-AB-62436 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: GLRX2, CGI-133, GRX2

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Background: The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human GLRX2 (NP_001230328.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 18 kDa

Molecular Weight(Observed): 18 kDa