Glucose 6 phosphatase alpha Polyclonal Antibody | BS65881

Glucose 6 phosphatase alpha Polyclonal Antibody | BS65881 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep,

Application: FCM,

Application Range: Flow-Cyt=0.2ug/test

Background: Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1) . This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]

Storage & Stability: Store at 4°C short term. Aliquot and store at -54°C long term. Avoid freeze-thaw cycles.

Specificity: Glucose 6 phosphatase alpha Polyclonal Antibody detects endogenous levels of Glucose 6 phosphatase alpha protein.

Molecular Weight: ~39 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: glucose-6-phosphatase, catalytic subunit; GSD1; AW107337; G-6-Pase; G6Pase; G6Pase-alpha; g6pc; G6PC_HUMAN; G6PT; Glucose-6-phosphatase alpha; Glucose-6-phosphatase; GSD1a; MGC163350; MGC93613; RP23-281C18.19.

Immunogen: KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha:81-180/357

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: