GLUT2 (SLC2A2) Antibody (N-term) [AMM04811G]

GLUT2 (SLC2A2) Antibody (N-term) [AMM04811G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GLUT2 (SLC2A2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human GLUT2 (SLC2A2) .

Cellular Localisation: Cell membrane; Multi-pass membrane protein

Molecular Weight: 57490

Clone: Polyclonal

Gene Name: SLC2A2 (HGNC:11006)

Gene ID: 6514

Function: Facilitative hexose transporter that mediates the transport of glucose and fructose (PubMed:8027028, PubMed:16186102, PubMed:23396969, PubMed:28083649) . Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell (PubMed:8027028) . May also participate with the Na (+) /glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (PubMed:3399500) . Also able to mediate the transport of dehydroascorbate (PubMed:23396969) .

Summary: Tissue Location: Liver, insulin-producing beta cell, small intestine and kidney.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Solute carrier family 2, facilitated glucose transporter member 2, Glucose transporter type 2, liver, GLUT-2, SLC2A2, GLUT2