Glutamate receptor 2 (Precursor) (phospho Ser880) Antibody | 79-494

Glutamate receptor 2 (Precursor) (phospho Ser880) Antibody | 79-494 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Glutamate receptor 2 (Precursor) (phospho-Ser880) antibody was raised against a peptide sequence around phosphorylation site of serine 880 (I-E-S (p) -V-K) derived from Human Glutamate receptor 2.

Research Area: Phospho-Specific, Neuroscience

Tested Application: WB

Application: Western Blot: 1:500~1:1000

Specificiy: This antibody detects endogenous level of Glutamate receptor 2 (Precursor) only when phosphorylated at serine 880.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 100 kDa

Validation: N/A

Isoform: N/A

Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/mL

Storage Condition: Store antibody at -20˚C for up to one year.

Alternate Name: GLUR2, GLURB, GluA2, HBGR2, GluR-K2, PI12, GRIA2, GluR-2, GluR-B, AMPA 2

User Note: N/A

BACKGROUND: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.