GM 6001 | 1799

Cell-permeable. A broad spectrum matrix metalloprotease (MMP) inhibitor with Ki values of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM, 0.36 nM for MMPs -1, -2, -3, -7, -8, -9, -12, -14, and -26, respectively.

GM6001 is a broad spectrum matrix metalloprotease (MMP) inhibitor with Ki values of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM, 0.36 nM for MMPs -1, -2, -3, -7, -8, -9, -12, -14, and -26, respectively.

1799 | GM 6001 DataSheet

Alternate Name/Synonyms: N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide; Galardin; Ilomastat

Appearance: White solid

Formulation: N/A

CAS Number: 142880-36-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₈N₄O₄

Molecular Weight: 388.46

Cell-Permeable?: Yes

Purity: ≥95% by TLC

Solubilities: DMSO (25 mM) or EtOH (10 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A broad spectrum MMP inhibitor

MDL Number: MFCD03453614

PubChem CID: 132519

SMILES: CC(C)CC(CC(=O)NO)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC

InChi: InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1

InChi Key: NITYDPDXAAFEIT-DYVFJYSZSA-N