GM-CSF Antibody [BVD2-21C11] | 33-116

GM-CSF Antibody [BVD2-21C11] | 33-116 | Gentaur UK, US & Europe Distribution

Host: Rat

Reactivity: Human, Cynomolgus, Rhesus

Homology: N/A

Immunogen: Recombinant human protein was used as the immunogen for this antibody.

Research Area: Immunology, Signal Transduction

Tested Application: WB, Flow, IHC, IF, IP, Neut

Application: Functional Activity (Neutralization) : neutralizes GM-CSF bioactivity
Flow Cytometry: 0.5-1 ug/million cells
IF: 0.5-1 ug/ml
WB: 0.5-1 ug/ml
IP: 0.5-1��g/500ug protein lysate
IHC (Frozen) : 0.5-1 ug/ml for 30 minutes at RT
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the GM-CSF antibody to be titered up or down for optimal performance.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein G affinity chromatography

Clonality: Monoclonal

Clone: BVD2-21C11

Isotype: IgG2a, kappa

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Concentration: 0.2 mg/mL

Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.

Alternate Name: Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF

User Note: Optimal dilutions for each application to be determined by the researcher

BACKGROUND: GM-CSF (Granulocyte/macrophage - Colony-stimulating factor) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.