Description
GNAQ Antibody | 15-694 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human GNAQ (NP_002063.2) .
Research Area: Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: DU145
Positive Control 2: OVCAR3
Positive Control 3: HT-29
Positive Control 4: U-251MG
Positive Control 5: LO2
Positive Control 6: Mouse brain
Molecular Weight: Observed: 42kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: GAQ, G-ALPHA-q, guanine nucleotide binding protein (G protein) , q polypeptide, GNAQ, GAQ
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.