GNAS Antibody (Center) [APR05815G]

GNAS Antibody (Center) [APR05815G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-667 amino acids from the Central region of human GNAS.

Cellular Localisation: Cell membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:Q63803}. Apical cell membrane

Molecular Weight: 111025

Clone: Polyclonal

Gene Name: GNAS

Gene ID: 2778

Function: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs) . Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:4000

Synonyms: Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas, Adenylate cyclase-stimulating G alpha protein, Extra large alphas protein, XLalphas, GNAS, GNAS1 {ECO:0000303|PubMed:9707596}