GNL2 Antibody (N-term) [APR31414G]

GNL2 Antibody (N-term) [APR31414G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GNL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human GNL2.

Cellular Localisation: Nucleus, nucleolus

Molecular Weight: 83655

Clone: Polyclonal

Gene Name: GNL2

Gene ID: 29889

Function: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) . May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195) .

Summary: Tissue Location: Widely expressed, with the highest expression level in testis.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Nucleolar GTP-binding protein 2, Autoantigen NGP-1, GNL2, NGP1