GNS Antibody | 19-199

GNS Antibody | 19-199 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: A synthetic peptide of human GNS

Research Area: Cancer, Cell Cycle, Signal Transduction

Tested Application: WB, IHC, Flow

Application: WB: 1:500 - 1:1000
IHC: 1:50 - 1:100
Flow: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 62kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, pH7.3.

Concentration: N/A

Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.

Alternate Name: N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome) . Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.