Goat Anti-Human beta-Catenin IgG Polyclonal Antibody | AB0095

Goat Anti-Human beta-Catenin IgG Polyclonal Antibody | AB0095 | Antibodies

Overview: Goat polyclonal antibody to Catenin (cadherin-associated protein), beta 1. Beta Catenin is a 88 kDa protein and is a key downstream effector in the Wnt signalling pathway. It is involved in early embryonic development and tumorigenesis. Beta Catenin is part of a complex of proteins that constitute adherens junctions, necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. This protein anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.

Other Names: cadherin-associated protein, CTNNB, CTNNB1, MRD19, armadillo antibody.

Other Names: cadherin-associated protein, CTNNB, CTNNB1, MRD19, armadillo antibody.

Concentration: 3 mg/ml

Antibody Type: Primary

Target Type: Anti-beta-Catenin

Accession Number: ENSG00000168036

Host Species: Goat

Immunogen Species: Human

Immunogen Type: Recombinant protein

Immunogen: Purified recombinant peptide derived from within residues 731 aa to the C-terminus of human beta Catenin produced in E. coli.

Isotype: IgG

Clonality: Polyclonal

Confirmed Reactive Species: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Specificity Detail: Detects a band of approximately 95 kDa by Western blot in MNT1 and SH-SY5Y cell lysates.

Buffer: PBS, 20% glycerol and 0.05% sodium azide

Purification: Epitope affinity purified

Conjugation: Unconjugated

Format: N/A

Application: WB, IF

Concentration/Dilution: WB:1:500-1:2,000, IF:1:50-1:250, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Storage: N/A

References: 1. Balashova OA, Visina O, Borodinsky LN. Development. 2017 Mar 2. PMID:28255006