Goat Anti-Human CX43 | AB0016

Goat Anti-Human CX43 IgG Polyclonal Antibody | AB0016 | Antibodies

Overview: Goat polyclonal to connexin 43, which is a member of the connexin family. Cx43 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. This protein is the major protein of gap junctions in embryonic development and in the heart that are thought to have a crucial role in the synchronized contraction of the heart.

Other Names: AVSD3, CX43, DFNB38, gap junction protein, alpha 1, 43kDa, GJA1, GJAL HSS, HLHS1, ODDD antibody.

Other Names: AVSD3, CX43, DFNB38, gap junction protein, alpha 1, 43kDa, GJA1, GJAL HSS, HLHS1, ODDD antibody.

Concentration: 4 mg/ml

Antibody Type: Primary

Target Type: Anti-CX43

Accession Number: ENSG00000152661

Host Species: Goat

Immunogen Species: Human

Immunogen Type: Recombinant protein

Immunogen: Purified recombinant peptide derived from within residues 230 aa to the C-terminus of rat CX43 produced in E. coli.

Isotype: IgG

Clonality: Polyclonal

Confirmed Reactive Species: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Specificity Detail: Detects endogenous levels of total connexin 43.

Buffer: PBS, 20% glycerol and 0.05% sodium azide

Purification: Epitope affinity purified

Conjugation: Unconjugated

Format: N/A

Application: WB, IF, IHC-P, IHC-F

Concentration/Dilution: WB:1:500-1:2,000, IF:1:50-1:250, IHC-P:1:250-1:800, IHC-F:1:250-1:800

Storage: N/A

References: 1. Catarino S, Ribeiro-Rodrigues TM, Sa Ferreira R, et al. Cells. 2020 Apr. PMID: 32272685, 2. Wang W, Ye S, Zhang L, et al. BMC Cardiovasc Disord 2020. PMID:32066388, 3. Barbeitos JP, MSc Thesis, University of Coimbra, Portugal 2018, 4. Martins-Marques T, Pinho MJ, Zuzarte M. et al. J Extracell Vesicles 2016 Sep. PMID:27702427, 5. Paiva RA, MSc Thesis, University of Coimbra, Portugal 2015, 6. Ferreira RRS, MSc Thesis, University of Coimbra, Portugal 2015, 7. Martins-Marques T, Anjo SI, Pereira P, et al. Mol Cell Proteomics 2015 Aug. PMID:26316108 Supplemental Information 8. Ribeiro-Rodrigues TM, Catarino S, Marques C, et al. FASEB J. 2014 Nov. PMID:25070368