GP6 Polyclonal Antibody | E-AB-19916

GP6 Polyclonal Antibody | E-AB-19916 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Glycoprotein 6, Glycoprotein VI, GP6, GPIV, GPVI, GPVI, MGC138168, Platelet collagen receptor, Platelet glycoprotein VI, Platelet glycoprotein VI precursor

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular

Background: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Concentration: 1.14 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human GP6

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A