Description
GP6 Polyclonal Antibody | E-AB-19916 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Glycoprotein 6, Glycoprotein VI, GP6, GPIV, GPVI, GPVI, MGC138168, Platelet collagen receptor, Platelet glycoprotein VI, Platelet glycoprotein VI precursor
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cardiovascular
Background: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Concentration: 1.14 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human GP6
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A