GPR145 polyclonal Antibody | BS62389

GPR145 polyclonal Antibody | BS62389 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat,Mouse

Application: WB IHC

Application Range: WB: 1:500~1000

Background: Heterogeneous nuclear ribonucleoprotein U-like protein 2, is a multifunctional protein and previous studies have implicated it in the modulation of p53 transcriptional activity, although this has been rather poorly understood. Results presented here demonstrate that hnRNPUL-1 represses p53 transcriptional activity and negatively regulates p21 levels. This is consistent with the depletion of hnRNPUL-1 leading to an increase in cells arrested in G1/S. Together these results confirm that hnRNPUL-1 acts as a p53 co-repressor with specific cellular targets.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: hnRNP UL2 polyclonal Antibody detects endogenous levels of hnRNP UL2 protein.

Molecular Weight: ~ 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Heterogeneous nuclear ribonucleoprotein U-like protein 2; Scaffold-attachment factor A2; SAF-A2; HNRNPUL2; HNRPUL2

Immunogen: Synthetic peptide, corresponding to Human hnRNP UL2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .

Pathway: