GPR166 polyclonal Antibody | BS62412

GPR166 polyclonal Antibody | BS62412 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat,Mouse

Application: WB

Application Range: WB: 1:500~1000

Background: The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the Septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. Septin 10, a 517 residue polypeptide which localizes to the cytoplasm and nucleus, shares closest homology to Septin 6 and Septin 8. Septin 10 is expressed ubiquitously, though most abundantly in the placenta, lung, kidney, heart, skeletal muscles, liver and various tumor cell lines. Like other Septin family members, Septin 10 displays GTP-binding and GTPase activity. Additionally, Septin 10 is potentially involved in cytokinesis. Upon maturation induced by lipopolysaccharide (LPS), dendritic cells express upregulated amounts of Septin 10.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Septin 3 polyclonal Antibody detects endogenous levels of Septin 3 protein.

Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Neuronal-specific septin-3; SEPTIN3; SEP3; SEPT3

Immunogen: Synthetic peptide, corresponding to Human Septin 3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .

Pathway: Nuclear Receptor Signaling,