BW
GPR174 polyclonal Antibody | BS62427
- SKU:
- BW-BS62427
- Availability:
- Usually ships in 5 working days
Description
GPR174 polyclonal Antibody | BS62427 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB IHC
Application Range: WB: 1:500~1000
Background: Mitochondrial polyribonucleotide nucleotidyltransferase, also designated 3'-5' RNA exonuclease, OLD35, PNPase or PNPT1, is an evolutionaly conserved protein in which the mouse protein shares 90% identity with the human version. PNPase participates in mRNA degradation and hydrolyzes single-stranded ribonucleotides in the 3' to 5' direction. PNPase forms homotrimers and is upregulated in response to interferon-β induction. The N-terminus of PNPase contains a putative mitochondrial targeting sequence; mutation analysis confirms that N-terminal sequences of PNPase target the protein to the mitochondria. Endogenous PNPase also co-localizes with a mitochondrial marker protein in HeLa cells.
Storage & Stability: Store at 4°C short term. Aliquot and store at -24°C long term. Avoid freeze-thaw cycles.
Specificity: PNPT1 polyclonal Antibody detects endogenous levels of PNPT1 protein.
Molecular Weight: ~ 88 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Polyribonucleotide nucleotidyltransferase 1, mitochondrial; 3'-5' RNA exonuclease OLD35; PNPase old-35; Polynucleotide phosphorylase 1; PNPase 1; Polynucleotide phosphorylase-like protein; PNPT1; PNPASE
Immunogen: Synthetic peptide, corresponding to Human PNPT1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Pathway: