GPR181 polyclonal Antibody | BS62436

GPR181 polyclonal Antibody | BS62436 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC

Application Range: WB: 1:500~1000

Background: The NDRG (N-Myc downstream-regulated gene) family consisting of NDRG1, NDRG2, NDRG3, and NDRG4 are structurally related proteins with roles in cell proliferation, differentiation, apoptosis, stress responses, and cell migration/metastasis. NDRG1 was originally identified as a protein that was upregulated in N-Myc knockout mice. Proteins in the NDRG family, particularly NDRG1 and NDRG2, have been reported to be down-regulated in various cancer tissues and have been suggested to function as a tumor suppressors. Members of the NDRG family each have distinct expression patterns; NDRG3 is most highly expressed in the testis, prostate, ovary, and brain. NDRG3 has also been shown to be up-regulated by androgen in prostate cell lines and can promote cell growth in those cells.

Storage & Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity: NDRG3 polyclonal Antibody detects endogenous levels of NDRG3 protein.

Molecular Weight: ~ 43 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

Immunogen: Synthetic peptide, corresponding to Human NDRG3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .

Pathway: