BW
GPR211 polyclonal Antibody | BS62472
- SKU:
- BW-BS62472
- Availability:
- Usually ships in 5 working days
Description
GPR211 polyclonal Antibody | BS62472 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB IHC
Application Range: WB: 1:500~1000
Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/ threonine (Ser/Thr) protein kinases. The salt-inducible kinases (SIKs) are a family of related serine-threonine kinases and are key enzymes that modulate important processes such as steroid hormone biosynthesis and Insulin signaling in adipocytes. QSK, also known as L19 or SIK3 (salt-inducible kinase 3), is a 1,263 amino acid cytoplasmic protein belonging to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and the AMPK subfamily. Ubiquitously expressed, QSK consists of one protein kinase domain and a UBA domain. QSK is activated by 14-3-3 ζ and utilizes magnesium as a cofactor. QSK exists as three alternatively spliced isoforms.
Storage & Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.
Specificity: QSK polyclonal Antibody detects endogenous levels of QSK protein.
Molecular Weight: ~ 140 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Serine/threonine-protein kinase SIK3; Salt-inducible kinase 3; SIK-3; Serine/threonine-protein kinase QSK; SIK3; KIAA0999; QSK; L19
Immunogen: Synthetic peptide, corresponding to Human QSK.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Pathway: