LBD
GPR62 Antibody (N-term) [APR14115G]
- SKU:
- LBD-APR14115G
- Availability:
- Usually ships in 5 working days
Description
GPR62 Antibody (N-term) [APR14115G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This GPR62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-87 amino acids from the N-terminal region of human GPR62.
Cellular Localisation: Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Colocalizes with ARRB2 in the endosome (PubMed:28827538) .
Molecular Weight: 37614
Clone: Polyclonal
Gene Name: GPR62
Gene ID: 118442
Function: Orphan G-protein coupled receptor. Constitutively activates the G (q/11) /inositol phosphate and the G (s) -alpha/cAMP signaling pathways (PubMed:28827538) . Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538) . Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538) .
Summary: Tissue Location: Expressed in brain; detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Probable G-protein coupled receptor 62, G-protein coupled receptor GPCR8, hGPCR8, G-protein coupled receptor KPG_005, GPR62