223

GPX1 Antibody | 13-911

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SKU:
223-13-911-GEN
$1,893.50

Description

GPX1 Antibody | 13-911 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-203 of human GPX1 (NP_000572.2) .

Research Area: Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: Mouse liver

Positive Control 3: Mouse kidney

Positive Control 4: Rat liver

Positive Control 5: Rat spleen

Positive Control 6: N/A

Molecular Weight: Observed: 22kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Glutathione Peroxidase 1; GSHPx-1; Cellular Glutathione Peroxidase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Additional Information

Size:
50 uL
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