Granzyme A, Human Recombinant | 4279

Granzyme A is a member of the granzyme family. Granzyme A is the most abundant serine protease in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A has a specific function in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262).

4279 | Granzyme A human recombinant DataSheet

Biomolecule/Target: Granzyme A

Synonyms: CTL tryptase, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, Granzyme-1, Hanukkah factor (H factor, HF)

Alternates names: Human transferrin, Siderophilin

Taglines: Serine proteases which induce apoptosis

NCBI Gene ID #: 7037

NCBI Gene Symbol: TFR1

Gene Source: Human

Accession #: P02786

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: > 90% as determined by SDS-PAGE

Assay #2: HPLC

Endotoxin Level: < 1.0 EU/g of protein as determined by LAL method

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 80.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from a 0.2 m filtered solution of 20 mM MES and150 mM NaCl, pH 5.5.

Reconstitution Instructions: Deionized HO (10 mg/ml)

Amino acid sequence: N/A