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Granzyme A, Human Recombinant | 4279
- SKU:
- 26-4279-GEN
- Availability:
- Usually shipped in 5 working days
Description
Granzyme A is a member of the granzyme family. Granzyme A is the most abundant serine protease in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A has a specific function in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262).
4279 | Granzyme A human recombinant DataSheet
Biomolecule/Target: Granzyme A
Synonyms: CTL tryptase, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, Granzyme-1, Hanukkah factor (H factor, HF)
Alternates names: Human transferrin, Siderophilin
Taglines: Serine proteases which induce apoptosis
NCBI Gene ID #: 7037
NCBI Gene Symbol: TFR1
Gene Source: Human
Accession #: P02786
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: > 90% as determined by SDS-PAGE
Assay #2: HPLC
Endotoxin Level: < 1.0 EU/g of protein as determined by LAL method
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 80.0 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized from a 0.2 m filtered solution of 20 mM MES and150 mM NaCl, pH 5.5.
Reconstitution Instructions: Deionized HO (10 mg/ml)
Amino acid sequence: N/A
Additional Information
Storage: |
Aliquot and store at -20°C or -80°C. Avoid repeated freeze thaw cycles. |
Shipping: |
Gel Pack |
Shelf Life: |
12 months |