GRINA Antibody | 7147

GRINA Antibody | 7147 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Mouse: (94%) , Rat: (94%) , Bovine: (83%)

Immunogen: Rabbit polyclonal GRINA antibody was raised against an 18 amino acid peptide near the center of human GRINA.
The immunogen is located within amino acids 110 - 160 of GRINA.

Research Area: Apoptosis

Tested Application: E, WB

Application: GRINA antibody can be used for detection of GRINA by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: GRINA antibody is predicted to not cross-react with other members of the TMBIM family.

Positive Control 1: Cat. No. 1313 - Human Testis Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 41 kDa

Validation: N/A

Isoform: N/A

Purification: GRINA Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: GRINA Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: GRINA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: GRINA Antibody: LFG1, HNRGW, TMBIM3, NMDARA1, LFG1, Protein lifeguard 1, NMDA receptor glutamate-binding subunit

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: GRINA Antibody: The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein) , TMBIM2/LFG (life guard) , TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1) , TMBIM4/GAAP (Golgi anti-apoptotic-associated protein) , and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein) . They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.